e-ISSN 2459-1726
Detection, characterization and antimicrobial susceptibility of Globicatella sanguinis isolated from endodontic infections in Ouagadougou, Burkina Faso [Turk Endod J]
Turk Endod J. Ahead of Print: TEJ-91300 | DOI: 10.14744/TEJ.2021.91300

Detection, characterization and antimicrobial susceptibility of Globicatella sanguinis isolated from endodontic infections in Ouagadougou, Burkina Faso

Wendpoulomdé Aimé Désiré Kaboré, Simavé René Dembélé, Nicolas Barro
Laboratory of Molecular Biology, Epidemiology and Surveillance of Bacteria and Viruses Transmitted by Food/Center for Research in Biological, Food and Nutritional Sciences/Graduate School of Science and Technology/ Joseph KI-ZERBO University, 03 BP 7021 Ouagadougou 03, Burkina Faso

Background: Globicatella sanguinis is an emerging pathogenic rarely recognized as a cause of infection. The objective of this work was to investigate the involvement of this bacterium in endodontic infections in Burkina Faso and to determine its susceptibility to antibiotics.
Materials and methods: It was a cross-sectional descriptive study conducted at the Municipal Oral Health Center of Ouagadougou, from June to October 2014. Clinical data were collected using a sheet. Bacteria were isolated by the method of streaking on selective medium and identification was done by API 20 Strep gallery. Antibiotic susceptibility was determined by the diffusion method on solid medium.
Results: A total of 125 patients were received with a significant proportion for the age group of 19 to 40 years (55.2%). Apical periodontitis accounted for 50.4% and endodontic cellulitis accounted for 49.6%. Five isolates of Globicatella sanguinis have been identified. They were resistant (100%) to cefotaxime, metronidazole and penicillin G. Spiramycin showed an intermediate sensitivity of 60%. Isolates showed good sensitivity (100%) to trimethoprim-sulfamethoxazole, amoxicillin-clavulanic acid and tazobactam-piperacillin. One of them produced extended spectrum β-lactamases.
Conclusion: The severity of infections that is responsible Globicatella sanguinis reflects difficulties to eradicate these bacteria from root canal system.

Keywords: Globicatella sanguinis, Endodontic infections, Antibiotic resistance



Corresponding Author: Wendpoulomdé Aimé Désiré Kaboré, Burkina Faso
Manuscript Language: English
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